Miami Rx Express Case Study

Key Results

  • 99.8%

    Signature capture compliance rate (up from 88%)

  • 87%

    Reduction in missed delivery disputes

  • 45 min

    Faster daily route completion per driver

  • 2+ hours

    Earlier arrival for time-sensitive medications

  • Zero

    Compliance audit findings for the first time

The Challenge

Miami Rx Express operates three pharmacy locations across Miami-Dade County, handling 120 to 180 prescription deliveries each day with a team of six drivers. For years, the operation ran on paper manifests, phone calls, and trust. It worked well enough until it didn’t.

Every morning, a pharmacy technician printed the day’s delivery list, sorted by zip code. That was the extent of the planning. Drivers received their stacks and chose their own stop order. The result was predictable: two drivers consistently cherry-picked nearby stops in Kendall and Coral Gables, while patients in Homestead and Florida City waited hours longer than necessary.

For most packages, a delay is an inconvenience. For prescription medication, it’s a different story entirely:

  • Insulin and refrigerated compounds sat in delivery vehicles well past their ideal handling window
  • Patients on strict medication schedules missed doses waiting for late deliveries
  • Time-sensitive prescriptions (antibiotics, post-surgical pain management) arrived hours after they were needed
  • No documented proof existed that the correct patient received the correct medication
  • Driver self-reporting was the only record of completed deliveries — no signatures, no photos, no timestamps

The breaking point came during a routine insurance audit. The auditor found that 12% of deliveries had no documented recipient confirmation. A patient had filed a non-receipt claim for a controlled substance, and the pharmacy had nothing to show except the driver’s word. The insurance company flagged the entire operation as a liability risk.


We had a patient say they never received their medication, and I had to tell our insurance company that our only proof was the driver saying he dropped it off. That’s when I realized we were one disputed delivery away from a serious problem.

Carlos Medina
Carlos Medina

Director of Pharmacy Operations, Miami Rx Express


The pharmacy needed a system that could do three things: optimize delivery routes so time-sensitive medications arrived first, capture verifiable proof of delivery at every stop, and generate compliance documentation that would satisfy an auditor.

The Solution

Carlos and his team evaluated several delivery management platforms, but most were built for package couriers or food delivery, not pharmacy operations where compliance documentation is non-negotiable. Upper stood out because it combined route optimization with mandatory proof of delivery workflows that could be configured to match pharmacy requirements.


We needed more than just faster routes. We needed a system that wouldn’t let a driver close out a stop without getting a signature. Most tools treat proof of delivery as optional. Upper lets us make it mandatory.

Carlos Medina
Carlos Medina

Director of Pharmacy Operations, Miami Rx Express


Morning Import: From Zip Code Sorting to Optimized Routes in Minutes

Each morning, the pharmacy management system exports the day’s deliveries as a CSV file. A pharmacy tech uploads it into Upper, and the platform builds optimized routes for all six drivers in under two minutes. The old process (printing manifests sorted by zip code and hoping drivers made smart decisions) is gone.

Upper’s route optimization factors in time windows, which changed everything for medication priority. Insulin deliveries, refrigerated compounds, and post-surgical prescriptions are tagged with tight delivery windows. The algorithm sequences these stops first, ensuring time-sensitive medications reach patients before less urgent prescriptions.

Drivers no longer choose their own order. Routes are dispatched to the driver app, and each driver follows the optimized sequence. The cherry-picking problem disappeared overnight.

Mandatory Signature Capture: No Signature, No Completion

The most important configuration for Miami Rx Express was Upper’s proof of delivery settings. The team set up a strict workflow: drivers cannot mark a stop as complete without capturing a recipient’s signature on the app. No workaround, no skip button, no exceptions.

For contactless deliveries, common during flu season and for immunocompromised patients, drivers capture a photo of the package at the doorstep along with a timestamped note. The system logs GPS coordinates, time of delivery, and the driver’s identity automatically.

One situation tested the system early on. A driver arrived at a patient’s home and the caregiver on-site wasn’t the named recipient. Under the old system, the driver would have left the medication and moved on. With Upper, the driver called the pharmacy, confirmed the caregiver was authorized, noted it in the app, and captured the caregiver’s signature. When the patient’s family later questioned the delivery, the pharmacy pulled up the full record in seconds.


That one incident justified the entire switch. We had the signature, the timestamp, the GPS location, and the driver’s note about the caregiver. Before Upper, we would’ve had nothing.

Carlos Medina
Carlos Medina

Director of Pharmacy Operations, Miami Rx Express


Patient Notifications: Fewer Calls, Better Experience

Before Upper, the pharmacist personally called patients to give rough delivery estimates, a task that consumed 30 to 45 minutes each morning. Now, Upper’s customer notification feature handles it automatically. Patients receive an email when their delivery is on the way, with a tracking link showing the driver’s progress and estimated arrival time.

The result was immediate. Inbound calls asking “Where’s my medication?” dropped significantly, freeing up pharmacy staff to focus on filling prescriptions instead of fielding delivery status questions.

End-of-Day Compliance Reports: Audit-Ready Documentation

At the end of each day, the operations team generates a PDF report from Upper’s analytics dashboard containing every delivery record: recipient signature or doorstep photo, GPS coordinates, timestamp, driver name, and delivery status. The report is filed digitally and backed up, ready for any insurance auditor, Board of Pharmacy inspector, or patient inquiry.

This single capability replaced a filing cabinet full of paper manifests that were, at best, incomplete and, at worst, useless for dispute resolution.

The Impact

Within 90 days of implementing Upper, Miami Rx Express transformed its delivery operation from an insurance liability into a compliance model. The pharmacy group passed its next insurance audit with zero findings, a first in the company’s history.

The numbers tell the story, but the operational shift runs deeper. Drivers follow optimized routes instead of making ad hoc decisions. Every delivery is documented. Time-sensitive medications arrive when patients need them. And the pharmacy has an evidence trail for every prescription that leaves the building.

Performance Metrics

Metric Before Upper After Upper
Signature capture rate 88% 99.8%
Monthly missed delivery disputes ~8 1
Time-sensitive medication arrival Mid-afternoon Before noon
Daily route completion time 7.5 hours avg 6.75 hours avg
Morning route planning time 45 minutes Under 5 minutes
Insurance audit findings Multiple Zero
Inbound “where’s my delivery” calls 15–20/day 3–5/day

The 45-minute reduction in daily route time per driver adds up to 22.5 hours saved across the fleet each week. That time translates directly into capacity for additional deliveries as the pharmacy group grows.

For Carlos and his team, the most meaningful change isn’t a metric. It’s confidence. When a patient calls about a delivery, the pharmacy can pull up the complete record (signature, photo, timestamp, location) in seconds. When an auditor walks in, the documentation is already waiting.


We went from dreading audits to welcoming them. Every delivery is documented, every signature is captured, and every time-sensitive medication gets where it needs to go on time. Upper didn’t just fix our routing — it fixed our entire delivery operation.

Carlos Medina
Carlos Medina

Director of Pharmacy Operations, Miami Rx Express